2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N5005
    Guanfu base H
    		Inhibitor 99.80%
    Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively.
    Guanfu base H
  • HY-118383
    Agathisflavone
    		Inhibitor 99.62%
    Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats.
    Agathisflavone
  • HY-N4184
    Licoflavone B
    		Inhibitor 99.91%
    Licoflavone B is a flavonoid isolated from Glycyrrhiza inflata, inhibits S. mansoni ATPase (IC50, 23.78 µM) and ADPase (IC50, 31.50 µM) activity. Anti-schistosomiasis activity.
    Licoflavone B
  • HY-N7897
    Myrrhone
    		Inhibitor 99.89%
    Myrrhone is a terpenoid compound with antiplasmodial effects.
    Myrrhone
  • HY-155354
    Antimalarial agent 33
    		Inhibitor 99.13%
    Antimalarial agent 33 (compound 5g) has antiplasmodial activity against erythrocytic and hepatic stages of Plasmodium with an EC50 of 1.1 μM for K1 P. falciparum strain. Antimalarial agent 33 demonstrats enhanced microsomal stability (T1/2=29 min). Antimalarial agent 33 has no significant cytotoxicity against primary hepatocytes.
    Antimalarial agent 33
  • HY-119614
    Niridazole
    		98.75%
    Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC50 values ranging from 0.0037 to 1.0 μg/mL.
    Niridazole
  • HY-N9991
    5-Hydroxy-3,7-dimethoxyflavone
    		Control 99.89%
    5-Hydroxy-3,7-dimethoxyflavone (compound 1) can be isolated from Kaempferia parviflora, but has no significant toxicity to malaria parasites, fungi, and bacteria.
    5-Hydroxy-3,7-dimethoxyflavone
  • HY-N0110A
    Palmatine
    		Inhibitor
    Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC50 of 96 μM. Palmatine shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities.
    Palmatine
  • HY-B0263S
    Thiabendazole-d4
    		98.84%
    Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].
    Thiabendazole-d<sub>4</sub>
  • HY-12641
    Pyrantel tartrate
    		Inhibitor 98.69%
    Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
    Pyrantel tartrate
  • HY-B0935S1
    Benzyl benzoate-d12
    		99.85%
    Benzyl benzoate-d12 is the deuterium labeled Benzyl benzoate[1]. Benzyl benzoate (Benzoic acid benzyl ester) is a fragrance ingredient in cosmetic products. Benzyl benzoate can be used for the research of Scabies and Demodex-associated inflammatory skin conditions[2][3][4].
    Benzyl benzoate-d<sub>12</sub>
  • HY-120696
    SR9186
    		Inhibitor 98.06%
    SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to block ivermectin metabolism.
    SR9186
  • HY-111934
    Cymarin
    Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant.
    Cymarin
  • HY-34204
    2'-Hydroxy-4'-methylacetophenone
    		99.47%
    2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone.
    2'-Hydroxy-4'-methylacetophenone
  • HY-157892
    Antimalarial agent 38
    		Inhibitor
    Antimalarial agent 38 (Compound 1) exhibits activity against antiplasmodial, which inhibits Plasmodium falciparum D6 strain, chloroquine-sensitive Thai strain and chloroquine-resistant FcB1 strain and K1 strain, with IC50s of 0.5, 13, 1 and 13 μM, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 (IC50 >140 μM). Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model.
    Antimalarial agent 38
  • HY-B1177
    Crotamiton
    		Inhibitor
    Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic.
    Crotamiton
  • HY-W010254
    4′-Hydroxy-2′-methylacetophenone
    		Inhibitor 99.99%
    4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM.
    4′-Hydroxy-2′-methylacetophenone
  • HY-B2029
    Phosalone
    		Inhibitor 98.51%
    Phosalone is a member of the organophosphate family of insecticides.
    Phosalone
  • HY-B0825
    (E)-Fenpyroximate
    		Inhibitor 99.81%
    (E)-Fenpyroximate is a potent acaricide.
    (E)-Fenpyroximate
  • HY-B1331
    Cyromazine
    		99.79%
    Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats.
    Cyromazine
Parasite Isoform Comparison

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